Actively Recruiting
Exercise to Improve Sleep in Parkinson's Disease
Led by McGill University · Updated on 2026-03-13
150
Participants Needed
3
Research Sites
330 weeks
Total Duration
On this page
Sponsors
M
McGill University
Lead Sponsor
J
Jewish Rehabilitation Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will investigate the impact of three common exercise modalities, cardiovascular, resistance, and multimodal (i.e., a combination of the previous two) training, on sleep quality and architecture in persons with Parkinson's disease (PD). Furthermore, the project will investigate whether the potential positive exercise-induced changes in sleep are associated with improvements in different quality of life (QoL)-related aspects. Participants will perform either cardiovascular training (CT), resistance training (RT), multimodal training (MT), or will be allocated to a control condition (i.e., waiting list - CON) for 12 weeks. Training will be performed three times/week. The assessments will be conducted at baseline, post-intervention, and follow-up (i.e. 8 weeks after the intervention) by assessors blinded to the participants' group allocation.
CONDITIONS
Official Title
Exercise to Improve Sleep in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Persons with mild-moderate idiopathic Parkinson's Disease (Modified Hoehn & Yahr Scale stages 0.5-3.5)
- On a stable dosage of medication during the previous month
- Having poor sleep quality defined as a score > 15 in the PDSS-2 and/or reporting subjective sleep complaints affecting their sleep quality
You will not qualify if you...
- Having atypical parkinsonism, dementia, stroke, or any other neurological condition
- Presenting severe untreated obstructive sleep apnea (OSA)
- Having a Montreal Cognitive Assessment (MoCA) score <18
- Having a Beck Depression Inventory score >31
- Having absolute contraindications to exercise
- Having severe osteoporosis
- Participating in an exercise or drug trial during the period of the study
- Exceeding the physical activity levels recommended for the general population (≥150 minutes/week of moderate-intensity or ≥75 minutes/week of vigorous-intensity cardiovascular activity) and/or strengthening activities ≥2 days/week
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 3 locations
1
Jewish Rehabilitation Hospital
Laval, Quebec, Canada, H7V 1R2
Actively Recruiting
2
Human Brain Control of Locomotion Laboratory
Montreal, Quebec, Canada, H2W 1S4
Actively Recruiting
3
Cummings Centre
Montreal, Quebec, Canada, H3W 3E8
Not Yet Recruiting
Research Team
M
Marc Roig, Ph.D.
CONTACT
C
Caroline Paquette, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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