Actively Recruiting
Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer
Led by University of Hull · Updated on 2025-02-04
30
Participants Needed
1
Research Sites
63 weeks
Total Duration
On this page
Sponsors
U
University of Hull
Lead Sponsor
H
Hull University Teaching Hospitals NHS Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a single arm feasibility study of exercise for improving long- course neoadjuvant chemoradiotherapy (NACRT) efficacy in people diagnosed with locally advanced rectal cancer. The study aims to recruit up to 30 patients from the Queen's Centre for Oncology and Haematology of Castle Hill Hospital, Cottingham, diagnosed with locally advanced rectal cancer. Consenting patients will be provided with an 11-week course of structured aerobic exercises and resistance training in the periods before, during and after their chemoradiotherapy treatment. The patients will be followed up for 6 months post long course neoadjuvant chemoradiotherapy (NACRT), with a total of 3 assessment periods.
CONDITIONS
Official Title
Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Diagnosed with locally advanced rectal cancer confirmed by MRI and histology
- Offered long-course neoadjuvant chemoradiotherapy at the Queens Centre, Castle Hill Hospital
- Willing and able to follow all study requirements
- Able and willing to give informed consent voluntarily
You will not qualify if you...
- Unable to understand basic written and spoken English
- Movement issues limiting ability to exercise
- Impaired cognition or capacity affecting informed consent
- Cardiovascular or cardiopulmonary conditions preventing safe exercise
- Severe psychiatric disorders
- Any health condition deemed by oncologists and research team to prevent safe exercise
- Presence of metastatic cancer
AI-Screening
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Trial Site Locations
Total: 1 location
1
Castle Hill Hospital
Cottingham, East Yorkshire, United Kingdom, HU16 7JQ
Actively Recruiting
Research Team
C
Chizitara Amadi
CONTACT
J
John Saxton
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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