Virtual Supervised Exercise Program for Adults with Indolent Metastatic Breast Cancer to Improve Fitness and Quality of Life

What this Trial Is About

Researchers are studying the effects of exercise in adults with indolent metastatic breast cancer who have not had disease progression in the past 12 months and are not receiving cytotoxic chemotherapy. The study aims to see if a 16-week virtual, supervised exercise program combining aerobic and resistance training can improve heart and lung fitness, physical function, muscle mass, and patient-reported quality of life measures. This trial is a randomized, two-arm study comparing exercise to usual care in this specific patient group. Participants are randomly assigned to either an exercise intervention or usual care. Those in the exercise group will work with a trainer three times a week for 16 weeks in virtual sessions lasting 60 minutes. Each session includes cardiovascular exercise, resistance training, and balance or stretching exercises, with intensity adjusted based on heart rate and perceived exertion. The usual care group receives standard care and educational handouts encouraging exercise but no structured program. Throughout the study, participants will undergo tests to measure cardiorespiratory fitness, physical performance, muscle and fat composition via CT scans, and physical activity tracking. Patient-reported outcomes like fatigue and quality of life will also be assessed at baseline, 8 weeks, and 16 weeks. Researchers will monitor adherence to the exercise program and evaluate changes in physical and patient-reported measures to understand the impact of the intervention over the 16-week period.

Exercise in Metastatic Breast Cancer: EMBody