Actively Recruiting
Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study
Led by Universita di Verona · Updated on 2025-06-29
324
Participants Needed
1
Research Sites
243 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The general goal of the STARLighT study is to test whether a structured physical exercise and nutritional intervention significantly impacts clinical outcomes in patients with early-stage lung cancer. The main questions it aims to answer are: * Can structured physical exercise and nutrition intervention positively modify the pathological complete response in patients with early-stage lung cancer undergoing neoadjuvant treatments? * Can structured physical exercise and nutrition intervention positively influence disease-free survival in patients with early-stage lung cancer undergoing adjuvant treatments compared to usual care? This study will recruit two cohorts of patients. Cohort A will accrue patients who are candidates for neoadjuvant treatment and offer the opportunity to participate in a structured physical exercise and nutritional program, lasting the entire period of anticancer treatment. Cohort B will accrue patients who are candidates for adjuvant treatments. Patients will be randomized to receive 6 months of structured physical exercise and nutritional intervention or standard of care.
CONDITIONS
Official Title
Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Confirmed diagnosis of resectable or resected non-oncogene addicted NSCLC (EGFR, ALK wild-type)
- Stage IB to IIIB lung cancer
- Candidate for or currently undergoing systemic treatment
- ECOG performance status of 0 or 1
- Provided written informed consent
- Willing to use the study's monitoring and support technology/device
You will not qualify if you...
- Medical conditions that absolutely contraindicate exercise, nutrition, or psychological intervention (e.g., heart failure, uncertain arrhythmia, uncontrolled hypertension, severe renal dysfunction, bone marrow insufficiency, reduced standing or walking ability, recent myocardial infarction)
- Need for or current use of artificial nutrition support due to severely compromised oral intake
- Unable or unwilling to consume oral nutritional supplements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Verona Hospital
Verona, Italy, 37131
Actively Recruiting
Research Team
A
Alice Avancini, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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