Actively Recruiting
Exercise and Nutrition for Older Cancer Survivors and Their Support Person: The Vitality Study
Led by Dana-Farber Cancer Institute · Updated on 2026-03-02
1528
Participants Needed
2
Research Sites
248 weeks
Total Duration
On this page
Sponsors
D
Dana-Farber Cancer Institute
Lead Sponsor
P
Patient-Centered Outcomes Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research study will compare the impact of virtually supervised and unsupervised home-based exercise and diet programs on cognitive and physical function among cancer survivors and support persons. This study will involve a 6-month home-based virtually supervised or unsupervised exercise and diet intervention. The names of the study interventions involved in this study are: * Virtually supervised exercise and healthy diet care * Unsupervised exercise and healthy diet care
CONDITIONS
Official Title
Exercise and Nutrition for Older Cancer Survivors and Their Support Person: The Vitality Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability and willingness to sign informed consent before any study procedures
- Cancer survivors aged 65 years or older
- Completed chemotherapy and/or targeted therapy within the past 36 months
- Diagnosed with breast, lung, prostate, or colorectal cancer
- No dementia as shown by a score of 23 or higher on the Telephone Interview for Cognitive Status
- Overweight or obese with BMI 25 kg/m2 or higher, or high body fat percentage
- Currently doing less than 60 minutes of structured moderate-to-vigorous exercise per week
- No history of disordered eating
- Living with an informal support person aged 18 or older willing to participate
- Able to speak English or Spanish
- Willing to travel to the study site for data collection
- Support persons must be adults 18 years or older
- Support persons have no dementia (score 23 or higher on TICS)
- Support persons have no history of disordered eating
- Support persons speak English or Spanish
You will not qualify if you...
- Cancer survivors younger than 65 years
- Survivors with a TICS score 22 or lower
- Survivors with BMI less than 25 kg/m2 and low body fat percentage
- Survivors already consuming a Mediterranean diet meeting 2 or more specific diet goals
- Survivors with unstable health conditions preventing moderate-to-vigorous exercise
- Survivors with severe psychiatric conditions like major depression, bipolar disorder, suicidal thoughts, or substance abuse
- Survivors unable to comply with safety monitoring
- Survivors currently undergoing treatment for active cancer (except basal cell carcinoma or hormone therapy)
- Support persons younger than 18 years
- Support persons with TICS score 22 or lower
- Support persons who are pregnant or plan pregnancy during the study
- Support persons with unstable health conditions preventing exercise
- Support persons with severe psychiatric conditions as listed above
- Support persons currently undergoing cancer treatment or within 10 years of treatment completion (except basal cell carcinoma)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Miami Sylvester Comprehensive Cancer Center
Miami, Florida, United States, 33136
Actively Recruiting
2
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
C
Christina Dieli-Conwright, PhD, MPH
CONTACT
J
Jordan Lane, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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