Actively Recruiting
Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2025-01-22
30
Participants Needed
1
Research Sites
49 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to determine what happens to the heart muscle contraction when people cycle before their hemodialysis treatment. Will pre-dialysis exercise protect the heart from a decrease in pumping of the heart muscle (called stunning) that can happen during hemodialysis. We will study whether pre-dialysis exercise decreases heart stunning, decreases the number and severity of symptoms commonly associated with hemodialysis, and other outcomes
CONDITIONS
Official Title
Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Must be on chronic hemodialysis for at least 3 months
- Age 18 years or older
- Willing and able to provide informed consent
- Assessed to be safe and able to exercise by unit HD Nephrologist
You will not qualify if you...
- Regular vigorous exercise outside of hemodialysis
- Over 79 years of age
- Intradialytic exercise less than 3 months
- Poor echogenicity
- Acute coronary syndrome in the past 3 months
- Unstable arrhythmia or angina
- Shortness of breath at rest or with minimal activity
- Symptomatic hypoglycemia more than twice per week in the week prior to enrollment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
London Health Sciences Centre
London, Ontario, Canada, N6A 5W9
Actively Recruiting
Research Team
J
Jarrin Penny, PhD, RN, CNeph (C)
CONTACT
K
Kathy Koyle
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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