Actively Recruiting

Age: 21Years - 100Years
All Genders
Healthy Volunteers
NCT05775484

Exercise to Slow Cardiovascular Ageing Progression

Led by National Heart Centre Singapore · Updated on 2025-06-05

450

Participants Needed

1

Research Sites

1443 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In ageing, deleterious alterations in cardiovascular (CV) structure and function increase risks of ageing-related cardiovascular disease (CVD). Investigators found that these CV alterations were associated with circulating serum metabolites, suggesting a metabolic basis to CV ageing. Investigators hypothesize that modification of these metabolites by intervention, such as exercise, may retard CV alterations and reduce CVD in ageing.

CONDITIONS

Official Title

Exercise to Slow Cardiovascular Ageing Progression

Who Can Participate

Age: 21Years - 100Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age >=21 years old
  • Able to walk outdoors
Not Eligible

You will not qualify if you...

  • Wheelchair or bed-bound
  • Dementia
  • Living in sheltered or nursing home
  • Cancer
  • Participation in ongoing clinical trials involving drugs or devices
  • Aneurysms
  • Acute infections in the last six months
  • Uncontrolled thyrotoxicosis
  • Neuromuscular, musculoskeletal, or rheumatoid disorders worsened by exercise
  • Uncontrolled asthma or chronic lung disease
  • Restrictive lung disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Heart Centre Singapore

Singapore, Singapore, Singapore, 169609

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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