Spontaneous coronary artery dissection: association with predisposing arteriopathies and precipitating stressors and cardiovascular outcomes.
Jacqueline Saw, Eve Aymong, Tara Sedlak...
https://pubmed.ncbi.nlm.nih.gov/25294399/Actively Recruiting
Led by University of Leicester · Updated on 2026-05-14
120
Participants Needed
1
Research Sites
21 weeks
Total Duration
This research aims to explore how a remote exercise program works for women recovering from spontaneous coronary artery dissection SCAD, a type of heart attack caused by a tear in the blood vessels. SCAD mostly affects otherwise healthy women and differs from traditional heart attacks. Since cardiac rehabilitation programs are typically designed for older populations, this study seeks to find out if a tailored remote exercise plan can be suitable and beneficial for these women. Participants are randomly assigned to one of two groups one group will receive a 12-week remote exercise program including a cardiopulmonary exercise test CPET and use of a wearable activity monitor the other group receives usual care along with a blinded wearable activity monitor. The study uses this design to safely prescribe exercise levels and monitor activity. The intervention aims to allow participants to achieve exercises that match their capacity, addressing concerns about exercise safety after SCAD. Women taking part will be monitored throughout the study with assessments at the start, during, and after the 12-week program, and at a 24-week follow-up. Researchers will collect data on recruitment, adherence to the program, acceptability, exercise duration and intensity, and self-efficacy. Additional measures include chest pain, mental wellbeing, anxiety, physical activity, and physical function tests like the 6-minute walk and sit-to-stand tests. The study helps understand recovery better and supports safe exercise practices after SCAD.
CONDITIONS
Exercise Support and Rehabilitation for Patients After Spontaneous Coronary Artery Dissection
N
Noemi Vadaszy, BSc, MSc, PhD
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
University of Leicester
Lead Sponsor
University Hospitals, Leicester
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for SCAD clinic appointment
Duration - 12 weeks
Participants in the exercise intervention group participate in a 12-week remote exercise program, including a cardiopulmonary exercise test (CPET) for safe exercise prescription and use of a wearable activity monitor.
1 baseline visit (CPET) and weekly remote exercise sessions with wearable activity monitoring
Duration - 12 weeks
Participants in the usual care group receive standard care and wear a blinded activity monitor during the 12-week period.
1 baseline visit and ongoing activity monitoring
Duration - Up to 24 weeks from intervention start
Participants are followed up 24 weeks after the start of the intervention to assess acceptability, exercise changes, and wellbeing.
1 follow-up visit (remote or in-person) at week 24
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Jacqueline Saw, Eve Aymong, Tara Sedlak...
https://pubmed.ncbi.nlm.nih.gov/25294399/Annie Y Chou, Roshan Prakash, Jennifer Rajala...
https://pubmed.ncbi.nlm.nih.gov/26923234/Karen Bouchard, Thais Coutinho, Jennifer Reed...
https://pubmed.ncbi.nlm.nih.gov/34435799/Hafiz Imran, Arlene Gaw, Loren Stabile...
https://pubmed.ncbi.nlm.nih.gov/33884107/Taryn C Silber, Marysia S Tweet, Melissa J Bowman...
https://pubmed.ncbi.nlm.nih.gov/25730096/Mariem A Sawan, Avery E Calhoun, Yetunde A Fatade...
https://pubmed.ncbi.nlm.nih.gov/35150655/Lindsey Anderson, Neil Oldridge, David R Thompson...
https://pubmed.ncbi.nlm.nih.gov/26764059/Marta Supervía, Jose R Medina-Inojosa, Colin Yeung...
https://pubmed.ncbi.nlm.nih.gov/28365100/Lis Neubeck, Sheona McHale, Mark Ross...
https://pubmed.ncbi.nlm.nih.gov/35290455/Coral L Hanson, Paul Kelly, Lis Neubeck...
https://pubmed.ncbi.nlm.nih.gov/33657530/University of Leicester
Lead Sponsor
University Hospitals, Leicester
Collaborating Sponsor