Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
ID06955663

Exercise Support and Rehabilitation for Patients After Spontaneous Coronary Artery Dissection - a Feasibility Study

Led by University of Leicester · Updated on 2026-05-14

120

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

Sponsors

U

University of Leicester

Lead Sponsor

U

University Hospitals, Leicester

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to explore how a remote exercise program works for women recovering from spontaneous coronary artery dissection (SCAD), a type of heart attack caused by a tear in the blood vessels. SCAD mostly affects otherwise healthy women and differs from traditional heart attacks. Since cardiac rehabilitation programs are typically designed for older populations, this study seeks to find out if a tailored remote exercise plan can be suitable and beneficial for these women. Participants are randomly assigned to one of two groups: one group will receive a 12-week remote exercise program including a cardiopulmonary exercise test (CPET) and use of a wearable activity monitor; the other group receives usual care along with a blinded wearable activity monitor. The study uses this design to safely prescribe exercise levels and monitor activity. The intervention aims to allow participants to achieve exercises that match their capacity, addressing concerns about exercise safety after SCAD. Women taking part will be monitored throughout the study with assessments at the start, during, and after the 12-week program, and at a 24-week follow-up. Researchers will collect data on recruitment, adherence to the program, acceptability, exercise duration and intensity, and self-efficacy. Additional measures include chest pain, mental wellbeing, anxiety, physical activity, and physical function tests like the 6-minute walk and sit-to-stand tests. The study helps understand recovery better and supports safe exercise practices after SCAD.

CONDITIONS

Brief Title

Exercise Support and Rehabilitation for Patients After Spontaneous Coronary Artery Dissection

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female
  • Aged 18 years or older
  • Diagnosed with angiographically confirmed SCAD
  • Referred to the Leicester SCAD clinic
  • Ejection fraction greater than 45%
  • Blood pressure below 180/100 mmHg and resting heart rate under 100 bpm
Not Eligible

You will not qualify if you...

  • No SCAD diagnosis
  • Unable to travel to Leicester Hospital for SCAD clinic appointment
  • Unable to give informed consent
  • No smartphone or internet access
  • Unable to understand verbal explanations in English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) for SCAD clinic appointment

Exercise Intervention

Duration - 12 weeks

Participants in the exercise intervention group participate in a 12-week remote exercise program, including a cardiopulmonary exercise test (CPET) for safe exercise prescription and use of a wearable activity monitor.

1 baseline visit (CPET) and weekly remote exercise sessions with wearable activity monitoring

Usual Care Monitoring

Duration - 12 weeks

Participants in the usual care group receive standard care and wear a blinded activity monitor during the 12-week period.

1 baseline visit and ongoing activity monitoring

Follow-up

Duration - Up to 24 weeks from intervention start

Participants are followed up 24 weeks after the start of the intervention to assess acceptability, exercise changes, and wellbeing.

1 follow-up visit (remote or in-person) at week 24

Trial Site Locations

Total: 1 location

1

University Hospitals of Leicester

Leicester, Leicestershire, United Kingdom, LE3 9QP

Actively Recruiting

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Research Team

N

Noemi Vadaszy, BSc, MSc, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Published Research Related To This Trial

The Contribution of Leisure Center Usage to Physical Activity in the United Kingdom: Evidence From a Large Population-Based Cohort.

Coral L Hanson, Paul Kelly, Lis Neubeck...

https://pubmed.ncbi.nlm.nih.gov/33657530

Spontaneous coronary artery dissection: a systematic review of physical and psychosocial recovery following discharge from hospital.

Lis Neubeck, Sheona McHale, Mark Ross...

https://pubmed.ncbi.nlm.nih.gov/35290455

The First Dedicated Cardiac Rehabilitation Program for Patients With Spontaneous Coronary Artery Dissection: Description and Initial Results.

Annie Y Chou, Roshan Prakash, Jennifer Rajala...

https://pubmed.ncbi.nlm.nih.gov/26923234

Secondary Preventative Care for Patients After Spontaneous Coronary Artery Dissection: A Qualitative Analysis of Health Care Providers' Perspectives.

Karen Bouchard, Chowdhury Nishwara Tarannum, Thais Coutinho...

https://pubmed.ncbi.nlm.nih.gov/32247705

Recovering from spontaneous coronary artery dissection: Patient-reported challenges and rehabilitative intervention needs.

Karen Bouchard, Thais Coutinho, Jennifer Reed...

https://pubmed.ncbi.nlm.nih.gov/34435799