Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
Healthy Volunteers
NCT07434349

Exercise Timing and Postprandial Glucose Responses

Led by Technical University of Munich · Updated on 2026-04-20

30

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This interventional crossover study examines the effect of exercise timing relative to meal intake on postprandial glucose responses in healthy, physically active young adults. Participants complete five experimental conditions involving endurance exercise performed before or after breakfast or dinner, as well as a non-exercise control condition, while wearing a continuous glucose monitoring device. Postprandial glucose responses are assessed for the three consecutive meals following each exercise session. Following morning exercise, outcomes are assessed after breakfast, lunch, and dinner on the same day. Following evening exercise, outcomes are assessed after dinner on the same day and after breakfast and lunch on the subsequent day. All meals are standardized and consumed at fixed clock times.

CONDITIONS

Official Title

Exercise Timing and Postprandial Glucose Responses

Who Can Participate

Age: 18Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 35 years
  • Body mass index 18.5 to 24.9 kg per square meter
  • Able to complete 45 minutes of continuous running at an intensity corresponding to 75 to 85 percent of maximal heart rate without stopping
  • Engages in regular endurance-type physical activity
  • Habitual waking times are compatible with the fixed breakfast time of 08:00
  • Willing and able to comply with all study procedures, including standardized meals, exercise sessions, behavioral restrictions, and continuous glucose monitoring
  • For female participants: non-pregnant and using stable hormonal contraception for at least 3 months
Not Eligible

You will not qualify if you...

  • Acute or chronic illness
  • Metabolic disorders or conditions associated with altered glucose or lipid metabolism
  • Use of medications known to interfere with glucose metabolism or study outcomes
  • Intolerance or allergy to components of the standardized study diets
  • Pregnancy or breastfeeding
  • Body mass index greater than or equal to 25 kg per square meter
  • Current or past eating disorder, or any medical condition or medication that could affect appetite regulation, glucose regulation, or make vigorous endurance exercise unsafe
  • Current smoking or use of nicotine-containing products

AI-Screening

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Trial Site Locations

Total: 1 location

1

Technical University of Munich

München, Bavaria, Germany, 80809

Actively Recruiting

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Research Team

C

Christoph Höchsmann, PD Dr.

CONTACT

K

Karsten Köhler, Prof. Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

5

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