Actively Recruiting
Exercise Training and Endothelial Function in Type 1 Diabetes
Led by University Hospital, Lille · Updated on 2026-05-14
34
Participants Needed
1
Research Sites
468 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological interventions to improve endothelial function appears fundamental. In this randomized controlled trial, the effects of exercise training on endothelial function will be evaluated in T1D adults. Secondary objectives are to evaluate the exercise training effects on the micro and macrovascular function and exercise-induced tissue vasoreactivity and their possible neurometabolic consequences. An improvement in vascular function, particularly endothelium-dependent, as well as in neurometabolic profile, through this non-pharmacological strategy is expected
CONDITIONS
Official Title
Exercise Training and Endothelial Function in Type 1 Diabetes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Covered by social security
- Diagnosis of type 1 diabetes for at least 1 year
- Free from macrovascular and microvascular diabetic complications
You will not qualify if you...
- Diagnosis of type 1 diabetes for less than 1 year
- Diagnosis of MODY diabetes, mitochondrial diabetes, or type 2 diabetes
- Presence of macrovascular and/or microvascular diabetic complications such as retinopathy, nephropathy, or neuropathy
- Obesity with Body Mass Index greater than 30 kg/m²
- Current smoker
- High blood pressure (hypertension)
- Disabling painful discomfort affecting trunk, upper, or lower limb movements
- Active chronic disease or disease in remission (excluding type 1 diabetes)
- History of head trauma in the past
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hop Claude Huriez Chu Lille
Lille, France, 59037
Actively Recruiting
Research Team
A
Anne Vambergue, MD,PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here