Actively Recruiting
Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation
Led by Ottawa Heart Institute Research Corporation · Updated on 2026-03-11
132
Participants Needed
2
Research Sites
988 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this project is to evaluate the effects of high-intensity interval training (HIIT) compared to moderate-intensity continuous exercise training (MICE) and standard care on exercise capacity and quality of life in patients with persistent or permanent atrial fibrillation. Positive findings are vitally important for these patients, given the condition's substantial morbidity, mortality and high economic costs.
CONDITIONS
Official Title
Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- persistent or permanent atrial fibrillation;
- rate controlled with a resting ventricular rate of equal to or less than 100 bpm;
- able to perform a symptom-limited exercise test;
- at least 40 years of age (i.e. participants must be 40 years or older);
You will not qualify if you...
- currently participating in routine exercise training (more than two times per week);
- unstable angina;
- diagnosed severe mitral or aortic stenosis;
- diagnosed hypertrophic obstructive cardiomyopathy with significant obstruction;
- pregnant, lactating or planning to become pregnant during the study period;
- unable to provide written, informed consent, or
- unwilling or unable to return for follow up at week 12.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
London Health Sciences Network
London, Ontario, Canada
Actively Recruiting
2
University of Ottawa Heart Insititue
Ottawa, Ontario, Canada, K1Y 4W7
Actively Recruiting
Research Team
J
Jennifer L Reed, PhD
CONTACT
M
Matheus Mistura, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here