Comparing Robotic, Exergame, and Standard Therapies to Improve Hand Function and Tenascin-C Levels in Stroke Patients

What this Trial Is About

This research investigates how different therapies compare in improving hand function for patients recovering from stroke. It focuses on three main interventions robotic therapy, exergame therapy using virtual reality, and standard rehabilitation. The study aims to evaluate the effectiveness of these treatments on functional recovery over time, changes in the blood protein Tenascin-C, and clinical outcomes among post-stroke patients. Participants will be randomly assigned to one of three groups standard rehabilitation involving physical therapy exercises, exergame therapy combining conventional therapy with virtual reality hand exercises, or robotic therapy combining conventional therapy with robotic-assisted hand exercises. All treatments are scheduled three times a week for six weeks, with assessments conducted before and after the treatment period. During the study, participants will undergo tests measuring upper extremity motor ability using the Fugl-Meyer Assessment, finger dexterity with the Nine Hole Peg Test, hand strength with a handgrip dynamometer, and Tenascin-C levels in the blood before and after therapy. Data collection includes interviews and physical exams, and progress will be tracked to compare the impact of each therapy. Safety and adherence will be monitored throughout the six-week training.

Exergame and Robotic Therapy Impact on Tenascin-C and Functional Outcome on Stroke Patients