Actively Recruiting
The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
Led by Children's National Research Institute · Updated on 2026-02-24
60
Participants Needed
1
Research Sites
125 weeks
Total Duration
On this page
Sponsors
C
Children's National Research Institute
Lead Sponsor
N
National Institute on Minority Health and Health Disparities (NIMHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to test the effectiveness and implementation of delivering Enhanced Brief Interpersonal Psychotherapy (IPT-B), an evidence-based maternal depression treatment, to mothers of children under the age of 18 in an urban pediatric asthma clinic. Researchers will compare Enhanced IPT-B and supplemented usual care (brief care coordination). The main questions the trial aims to answer are: 1. Does Enhanced IPT-B decrease maternal depressive symptoms? 2. Does Enhanced IPT-B improve child asthma management and health outcomes (exacerbations, symptoms, control)? 3. What are the preliminary implementation outcomes of delivering Enhanced IPT-B in an urban pediatric asthma clinic?
CONDITIONS
Official Title
The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be a female (self-identified) primary caregiver of a child with asthma seen at the community-based asthma clinic
- Self-identify as Black
- Be 18 years of age or older
- Speak English
- Have a PHQ-9 score of 8 or higher during depression screening at the child's clinic visit
- Have a child under 18 years old during the 6-month study period
- Child must be publicly insured
- Child must have physician-diagnosed persistent asthma
You will not qualify if you...
- Maternal acute suicidality (high risk on the C-SSRS at child's clinic visit)
- Maternal bipolar disorder or mania
- Maternal schizophrenia
- Current maternal substance abuse or dependence
- Current serious physical intimate partner violence
- Lack of capacity to participate meaningfully in study procedures as assessed during screening
- Child has significant medical co-morbidity such as cardiorespiratory disorders, developmental delay, diabetes, seizure disorder, or sickle cell disease
- Child is enrolled in another intervention with a behavioral component or novel asthma therapeutics
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children's National Hospital
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
Research Team
G
Geraldine Mendez-Gonzalez
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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