Actively Recruiting

Age: 0 - 22Years
All Genders
NCT04461821

Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry in Children and Adolescents

Led by University Children's Hospital Basel · Updated on 2026-05-08

3600

Participants Needed

1

Research Sites

511 weeks

Total Duration

On this page

Sponsors

U

University Children's Hospital Basel

Lead Sponsor

S

Swiss National Science Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is to investigate breath analysis (breath metabolomics) combined with established bioinformatic tools as a platform for companion diagnostics.

CONDITIONS

Official Title

Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry in Children and Adolescents

Who Can Participate

Age: 0 - 22Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 0 to 22 years at study entry with signed informed consent
  • For respiratory diseases: acute signs of respiratory illness like cough, wheezing, or increased breathing effort
  • For respiratory diseases: suspected or confirmed chronic airway disease such as asthma
  • For neurological disorders: acute neurological symptoms within 24 hours such as motor, sensory, or verbal deficits
  • For neurological disorders: confirmed chronic neurological disease like childhood epilepsy
  • For type 1 diabetes: acute hyperglycemia or acid-base imbalance related to new or known diabetes
  • For type 1 diabetes: confirmed diagnosis of type 1 diabetes
Not Eligible

You will not qualify if you...

  • Physical or intellectual impairment preventing study participation
  • For respiratory diseases: known cancer, active smoker (passive smoke exposure allowed), inflammatory diseases requiring treatment, or significant congenital defects
  • For neurological disorders: known cancer, active smoker (passive smoke exposure allowed), inflammatory diseases requiring treatment, or significant congenital defects
  • For type 1 diabetes: known cancer, active smoker (passive smoke exposure allowed), or significant congenital defects

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Children's Hospital Basel (UKBB)

Basel, Switzerland, 4031

Actively Recruiting

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Research Team

P

Pablo Sinues, Prof. Dr.

CONTACT

M

Mélina Richard

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

12

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Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry in Children and Adolescents | DecenTrialz