Actively Recruiting
Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients
Led by The Institute of Molecular and Translational Medicine, Czech Republic · Updated on 2026-03-23
200
Participants Needed
2
Research Sites
200 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Mechanically ventilated intensive care patients will be sampled for a small amount of exhaled breath condensate from the ventilator circuit and for venous blood. Proteomic analysis of the exhaled breath condensate will be performed using mass spectrometry and in the blood sample, corresponding changes in the DNA, RNA, proteins, and metabolites will be studied. Resulting profiles will be correlated with routinely monitored parameters in order to identify patterns corresponding to various pathologies in order to enable their early detection.
CONDITIONS
Official Title
Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient is in an intensive care setting
- Patient is receiving mechanical ventilation
- Ventilator or ventilator circuit is technically suitable for sampling exhaled breath condensate
You will not qualify if you...
- Mechanical ventilation is unstable or challenging such that inserting the sampling kit would risk respiratory deterioration
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Institute of Molecular and Translational Medicine, Palacky University
Olomouc, Czechia, 77900
Actively Recruiting
2
University Hospital Olomouc
Olomouc, Czechia, 77900
Actively Recruiting
Research Team
E
Emil Berta, MD PhD
CONTACT
K
Karel Axmann, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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