Actively Recruiting
Exogenous Ketone Esters for Refractory Status Epileptics
Led by Sohag University · Updated on 2024-11-27
50
Participants Needed
1
Research Sites
129 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate the efficacy of add-on exogenous ketone esters for the treatment of children with refractory generalized convulsive status epilepticus
CONDITIONS
Official Title
Exogenous Ketone Esters for Refractory Status Epileptics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Refractory generalized convulsive status epilepticus
You will not qualify if you...
- Failure to obtain informed consent
- Recent intake of exogenous ketones, ketogenic diet, or any dietary restrictions/modifications
- Hemodynamic or cardio-respiratory instability
- Traumatic brain injury
- Hypo- or hyperglycemia
- Metabolic acidosis
- Ketosis (βHB > 2 mmol/L)
- Associated severe disease condition, including hepatic, renal, respiratory, cardiac, gastrointestinal, endocrinal, and immune systems
- Malnutrition or obesity
- Limitations to nasogastric tube feeding
- Inborn errors of metabolism
- Allergies or any other contraindication to exogenous ketone esters
- Current or recent (within the last 24 hours) propofol therapy
- Intake of carbonic-anhydrase inhibitors
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Pediatrics at Sohag University Hospital
Sohag, Egypt, 82524
Actively Recruiting
Research Team
E
Elsayed M Abdelkreem, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here