Actively Recruiting

Age: 20Years - 75Years
All Genders
Healthy Volunteers
NCT06771427

Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome

Led by Taipei Veterans General Hospital, Taiwan · Updated on 2025-01-17

220

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

By analyzing the differential proteins in exosomes, this study aims to understand the pathological mechanisms of SJS and DES, identify potential diagnostic and therapeutic methods, and advance the diagnosis and treatment of these diseases.

CONDITIONS

Official Title

Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome

Who Can Participate

Age: 20Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 20 and 75 years
  • For Dry Eye Syndrome: Schirmer's test less than 10 mm/5 min
  • For Sjogren's Syndrome: primary or secondary diagnosis fulfilling the 2002 American-European Consensus Criteria
  • No abnormal immune, liver, kidney, or blood function evaluations for Sjogren's Syndrome
  • For healthy controls: aged between 20 and 75 years without any chronic disease
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Eye inflammation or infectious eye disease
  • History of eye surgery
  • History of alcohol abuse
  • Diabetes mellitus
  • Major life-threatening conditions
  • Steroid pulse therapy within three months before study start
  • For healthy controls: any diagnosis of Sjogren's Syndrome or Dry Eye Syndrome

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ching-Mao

Taipei, Taiwan, Taiwan, 886

Actively Recruiting

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Research Team

C

Ching-Mao Chang, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome | DecenTrialz