Actively Recruiting
Expanded Haploidentical Natural Killer Cells as Consolidation Strategy for Children/Young Adults With AML
Led by Belarusian Research Center for Pediatric Oncology, Hematology and Immunology · Updated on 2024-08-28
15
Participants Needed
1
Research Sites
239 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to estimate the efficacy of immunotherapy with ex vivo expanded haploidentical NK cells as consolidation therapy for children/young adults with intermediate risk AML.
CONDITIONS
Official Title
Expanded Haploidentical Natural Killer Cells as Consolidation Strategy for Children/Young Adults With AML
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with primary intermediate risk AML in molecular complete remission
- Patients with primary high risk AML in molecular complete remission awaiting unrelated hematopoietic stem cell transplantation
- Karnofsky or Lansky performance score of 70 or higher
- Written informed consent from patient or guardian
- Haploidentical family donor available
- Donor suitable for cell donation and apheresis according to standard criteria
- Written informed consent from donor
You will not qualify if you...
- Uncontrolled infection in patient
- Severe liver dysfunction with SGOT or SCPT 5 times or more above the upper limit for age
- Positive serology for HIV in patient
- Donor pregnancy
- Donor positive serology for HIV, hepatitis B, or hepatitis C
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Belarussian Research Center for Pediatric Oncology, Hematology and Immunology
Minsk, Minsk Oblast, Belarus, 223053
Actively Recruiting
Research Team
T
Tatsiana Shman, PhD
CONTACT
M
Mariya Naumovich, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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