Actively Recruiting
Expanding Medication-Assisted Therapies in Central Asia
Led by Yale University · Updated on 2025-09-22
900
Participants Needed
4
Research Sites
177 weeks
Total Duration
On this page
Sponsors
Y
Yale University
Lead Sponsor
D
Den Sooluk Nuru
Collaborating Sponsor
AI-Summary
What this Trial Is About
Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to scale-up OAT in three diverse Central Asian countries (Kazakhstan, Kyrgyzstan, Tajikistan) and guided by the Exploration-Planning-Implementation-Sustainment (EPIS) framework. Understanding the trajectories of implementation and scale-up in this context may emerge through creating communities of practice, especially when cohesion and competence evolves, and may guide other healthcare delivery challenges in the region (e.g., HIV, TB); as well as build important regional expertise and understanding implementation trajectories should help support OAT program sustainability.
CONDITIONS
Official Title
Expanding Medication-Assisted Therapies in Central Asia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be 18 years or older
- For people who inject drugs (PWID): meet DSM-V criteria for opioid dependence
- For PWID: be treatment naive and seeking OAT or have been on OAT for less than 90 days
- For OAT delivery staff: currently working as a professional at an OAT delivery site
- For Chief Narcologists: currently assigned as a Chief Narcologist for an Oblast
- For professionals: authorized to work at an OAT delivery site
You will not qualify if you...
- Not willing to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Yale University
New Haven, Connecticut, United States, 06510
Active, Not Recruiting
2
Columbia University Global Health Research Center of Central Asia
Almaty, Kazakhstan
Actively Recruiting
3
Den Sooluk Nuru
Bishkek, Kyrgyzstan
Actively Recruiting
4
Institute for International Health and Education
Dushanbe, Tajikistan
Actively Recruiting
Research Team
F
Frederick L Altice, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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