Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07206017

Explorative Study on Addition of High-fiber Dried Chicory Root in Patients With an Intermediate to High-risk Cutaneous Melanoma.

Led by University Medical Center Groningen · Updated on 2025-10-03

20

Participants Needed

1

Research Sites

128 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Exploring the effect of supplementation with daily addition of prebiotic dried chicory root (WholeFiberTM) for 6 weeks on fecal SCFA levels, gut microbial composition and immune cell composition in minimal stage II A melanoma patients following surgical treatment.

CONDITIONS

Official Title

Explorative Study on Addition of High-fiber Dried Chicory Root in Patients With an Intermediate to High-risk Cutaneous Melanoma.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age �318 years
  • Understands the study and can give written informed consent
  • Received surgical treatment for intermediate to high-risk cutaneous melanoma (Stage II A)
  • Able to read and speak Dutch
  • Willing to visit the UMCG study site
  • Willing to maintain regular lifestyle during the study
Not Eligible

You will not qualify if you...

  • Receiving adjuvant treatment during the study (adjuvant treatment after the study is allowed)
  • Medical history affecting study outcomes such as diabetes type 2, heart, kidney, or autoimmune diseases
  • Clinically significant or unstable gut disorders including celiac disease, inflammatory bowel disease, short-bowel syndrome, or pancreatitis
  • Having an ileostomy or colostomy
  • Use of antibiotics in the 3 months before the study
  • Use of prednisolone or other immunosuppressive drugs
  • Use of tube feeding or sip-feeding
  • Pregnant or breastfeeding
  • Participating in another interventional study at the same time
  • Unable or unwilling to follow study rules

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UMCG

Groningen, Provincie Groningen, Netherlands, 9713 GZ

Actively Recruiting

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Research Team

G

G. A.P. Hospers, MD, PhD

CONTACT

E

Emily Oosterhout, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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