Actively Recruiting
Exploratory Analysis of Enhanced Liver Function (ELF) Test to Detect Early Fatty Liver in High Risk Population
Led by Methodist Health System · Updated on 2026-05-13
300
Participants Needed
1
Research Sites
157 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this initial investigator-initiated retrospective study, aim to analyze the enhanced liver fibrosis (ELF) scores in this high-risk population for NAFLD/nonalcoholic steatohepatitis(NASH)-related fibrosis. Study define 'high-risk' to include metabolic syndrome, which can be further defined by an atherosclerotic cardiovascular disease (ASCVD) score \>7.5, any diagnosis of hyperlipidemia, history of coronary artery disease, history of heart failure, hypertension and/or type 2 diabetes. Study would also like to compare the performance of this score with historical methods of fibrosis assessment, where applicable, including vibration-controlled transient elastography, magnetic resonance elastography, blood markers and liver biopsy. Study will assess the impact of ELF scores on predicting liver events in the time, have used it and determine if diet, lifestyle changes and/or pharmacotherapy will improve serial ELF scores. Will also seek to understand how ELF scores are distributed in our community.
CONDITIONS
Official Title
Exploratory Analysis of Enhanced Liver Function (ELF) Test to Detect Early Fatty Liver in High Risk Population
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Patients with NAFLD/NASH or without NAFLD/NASH who had an ELF score assessment at Methodist Dallas Medical Center from November 2021 to December 2023
You will not qualify if you...
- Patients with incomplete data
- Patients lost to follow-up
AI-Screening
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Trial Site Locations
Total: 1 location
1
Methodist Dallas Medical Center
Dallas, Texas, United States, 75203
Actively Recruiting
Research Team
C
Crystee Cooper
CONTACT
J
Jennifer Kirchner
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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