Actively Recruiting

Age: 19Years +
All Genders
NCT06907160

Exploratory Biomarker Analysis of Neoadjuvant Chemoimmunotherapy Followed by Pulmonary Resection in Stage II-III Non-Small Cell Lung Cancer

Led by Yonsei University · Updated on 2025-04-02

100

Participants Needed

1

Research Sites

255 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

1. To explore tissue-based biomarkers to select patients who do not respond to neoadjuvant immunotherapy (non-responders) at the point of diagnosis 2. To explore blood-based non-invasive biomarkers to predict pathological complete response (pCR) before surgery

CONDITIONS

Official Title

Exploratory Biomarker Analysis of Neoadjuvant Chemoimmunotherapy Followed by Pulmonary Resection in Stage II-III Non-Small Cell Lung Cancer

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically proven clinical stage II-III lung cancer patients
  • No driver mutations (EGFR mutation and ALK alteration)
  • Whole body performance (ECOG) 0-1
  • Those over 19 years of age
  • Subject who submitted Informed consent form
Not Eligible

You will not qualify if you...

  • Under 19 years of age
  • History of infection or serious medical problems that impair function and compliance
  • Patients judged unable to comply with trial procedures and requirements
  • Other patients deemed unsuitable by the clinical trial director, including pregnant women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Thoracic and Cardiovascular Surgery, Severance Hospital, Yonsei University College of Medicine

Seoul, South Korea

Actively Recruiting

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Research Team

T

Tae Hee Hong

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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