Actively Recruiting
Exploratory Clinical Study on Fasting in Psoriasis and Psoriatic Arthritis (RiseFast)
Led by Charite University, Berlin, Germany · Updated on 2025-04-01
30
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
Sponsors
C
Charite University, Berlin, Germany
Lead Sponsor
M
Max Delbrück Center for Molecular Medicine (MDC), Berlin
Collaborating Sponsor
AI-Summary
What this Trial Is About
The RiseFast pilot study will investigate the clinical, metabolic and immunological effects of fasting and plant-based diet (PBD) on patients with psoriasis (PsO) and psoriatic arthritis (PsA) on their gut microbiota. The project will combine clinical assessments, cytometric profiling, and gut microbiota analysis to explore the relationship between fasting, a plant-based diet, and psoriatic disease. The study includes a 7-day fasting period followed by 11 weeks of PBD, with the goal of improving disease activity, quality of life, and understanding the role of gut microbiota in these conditions. This approach could lead to low-cost, accessible therapeutic options with minimal side effects.
CONDITIONS
Official Title
Exploratory Clinical Study on Fasting in Psoriasis and Psoriatic Arthritis (RiseFast)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Active plaque psoriasis (PASI 653) or psoriatic arthritis meeting CASPAR criteria and not meeting minimal disease activity criteria
- Stable psoriatic treatment for at least 12 weeks before enrollment
- Age 18 years or older
You will not qualify if you...
- Pregnancy or breastfeeding
- Underweight with BMI less than 18.5
- Eating disorder within the last 5 years
- Severe internal diseases such as renal insufficiency with creatinine over 2 mg/dl
- Current practice of vegan diet or fasting within the past 6 months
- Use of antibiotics within the past 3 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Charité - Universitätsmedizin Berlin, Psoriasis-Forschungs- und BehandlungsCentrum
Berlin, State of Berlin, Germany, 10117
Actively Recruiting
Research Team
A
Anika Rajput Khokhar, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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