Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05895981

Exploratory Clinical Trial of Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis.

Led by Xijing Hospital · Updated on 2025-12-04

15

Participants Needed

1

Research Sites

227 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Although the incidence of inflammatory bowel disease is stable in North American and European countries, the incidence of inflammatory bowel disease is increasing in newly industrialized countries, especially in China. The treatment drugs for ulcerative colitis include 5-aminosalicylic acid (5-ASA), glucocorticoids, immunosuppressants, and biological agents. The aim of this exploratory Clinical Trial is to evaluate the safety and efficacy of sacral nerve stimulation in patients with ulcerative colitis.

CONDITIONS

Official Title

Exploratory Clinical Trial of Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosed with ulcerative colitis for at least 3 months
  • Mayo score between 6 and 12, with Mayo endoscopic score of 2 to 3 points
  • Resistant to medical treatment
Not Eligible

You will not qualify if you...

  • No previous treatment for ulcerative colitis (treatment-naive)
  • Acute severe ulcerative colitis
  • Currently taking biological medications
  • Previous surgery or severe colitis requiring imminent surgery
  • Infective colitis
  • Other systemic diseases
  • Pregnancy or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xijing Hospital

Xi'an, Shaanxi, China, 710032

Actively Recruiting

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Research Team

J

Jian Wan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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