Actively Recruiting
An Exploratory Study of Cluster of Differentiation 38 (CD38) Monoclonal Antibody Combined Corticosteroid in Acquired Hemophilia A
Led by Institute of Hematology & Blood Diseases Hospital, China · Updated on 2025-08-05
25
Participants Needed
1
Research Sites
231 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the time of response, sustained remission rate and relapse rate of CD38 monoclonal antibody (Daratumumab) combined corticosteroid in the treatment of AHA. To evaluate the safety of CD38 monoclonal antibody in the treatment of AHA.
CONDITIONS
Official Title
An Exploratory Study of Cluster of Differentiation 38 (CD38) Monoclonal Antibody Combined Corticosteroid in Acquired Hemophilia A
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Acquired Hemophilia A (AHA)
- Women must be postmenopausal or use strict contraception if of childbearing age
- Patients must have good compliance with study requirements
You will not qualify if you...
- Diagnosis of congenital hemophilia with inhibitor
- Pregnant or lactating women
- Positive for hepatitis B surface antigen, hepatitis C antibody, HIV antibody, or syphilis antibody
- Poor compliance with study requirements
- Inability to use contraception during the trial
- Patients deemed unsuitable by researchers for any other reason
- Received immunosuppressive therapy within 4 weeks before enrollment with less than 50% decrease in inhibitor
- Presence of acquired von Willebrand disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Chinese Academy of Medical Science and Blood Disease Hospital
Tianjin, China
Actively Recruiting
Research Team
W
Wei Liu
CONTACT
L
Lei Zhang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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