Actively Recruiting
Exploratory Study of MRI Biomarkers of NASH
Led by University Hospital, Angers · Updated on 2025-09-30
60
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Angers
Lead Sponsor
A
Angers University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Metabolic steatosis disease (NAFLD) is a rapidly growing disease in the world, particularly in industrialized countries. NAFLD is defined by the presence of fatty liver disease. This is a reversible phenomenon that can be estimated by non-invasive means, such as ultrasound. Non-invasive quantification, on the other hand, requires MRI. Nonalcoholic steatohepatitis (NASH) is the aggressive form of the disease that promotes the accumulation of fibrosis in the liver, which can progress to cirrhosis and its complications. Currently there is no non-invasive biomarker of NASH and the diagnosis is based solely on liver biopsy. There is therefore a need for non-invasive biomarkers of NASH in patients with steatosis to diagnose NASH without the use of liver biopsy.
CONDITIONS
Official Title
Exploratory Study of MRI Biomarkers of NASH
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient included in the SNIFF cohort of the Angers hospital with suspected NASH requiring biopsy and MRI requested by a hepatologist
- Adult patient
- Provided free, informed, and oral consent to participate in the study
You will not qualify if you...
- Contraindication to MRI
- Time between Steatosis/NASH diagnosis and MRI longer than 3 months
- Pregnant, parturient, or breastfeeding women
- Persons deprived of liberty by judicial or administrative decision
- Persons under compulsory psychiatric care
- Persons under legal protection measures
- Persons not affiliated with or covered by a social security scheme
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University Hospital, Angers
Angers, France, France, 49000
Actively Recruiting
Research Team
A
Anita PAISANT, MD
CONTACT
A
Anthéa LOIEZ
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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