Actively Recruiting
Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening
Led by Centre Hospitalier Universitaire de Besancon · Updated on 2026-03-16
400
Participants Needed
3
Research Sites
591 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Colorectal cancer (CRC) is the third most common cancer in men and the second in women with an incidence of 43,350 new cases in 2018. This incidence is increasing every year. Early detection is crucial in this pathology. In France, free screening is organized by health insurance for people aged 50 to 74 years. This screening is based on an immunological test (FIT: Fecal Immunological test), which aims to detect the presence of blood in the stool. In fact, some polyps or cancers cause bleeding that is often minimal and therefore difficult or even impossible to detect with the naked eye. If this test is positive, a colonoscopy is done to check whether or not abnormalities are present in the colon or rectum. Performed under anesthesia, this examination can detect the possible presence of polyps or cancer. Recently, with the covid-19 epidemic, the investigators were faced with an extension of the delays for colonoscopies which led to delays in patient care. To prevent this, they propose to develop a blood test that would allow rapid identification of patients with colorectal cancer, requiring rapid management. This blood test will permit to have a parameter for stratifying the therapeutic care in the event of epidemia or situation that constrains the organisation of the health system.
CONDITIONS
Official Title
Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged more than18 years
- Cohort A: Patients with suspected colorectal cancer after a positive immunological stool test or visible bleeding
- Cohort B: Patients diagnosed with adenocarcinoma by pathology before surgery and candidates for colorectal tumor surgery
- Signed and dated informed consent
- Affiliated to or beneficiary of the French social security system
You will not qualify if you...
- Vulnerable persons according to the law (minors, adults under protection, persons deprived of liberty)
- Unable to comply with the study protocol as judged by the Investigator
- Pregnant women
- Currently excluded from another study
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Trial Site Locations
Total: 3 locations
1
CHU de Besançon
Besançon, France
Actively Recruiting
2
Hôpital Nord-Franche-Comté
Montbéliard, France
Not Yet Recruiting
3
Centre Hospitalier Intercommunal de Haute-Saône
Vesoul, France
Not Yet Recruiting
Research Team
C
Christophe BORG, Pr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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