Study of Oral Vitamin C to Support Healthy Aging in Adults Aged 55 to 65 Compared to Placebo and Healthy Controls Aged 18 to 70

What this Trial Is About

Researchers are investigating whether oral vitamin C can help slow aging in middle-aged and elderly adults. The study aims to find sensitive biomarkers of aging and provide scientific guidance for aging interventions using small molecule drugs. Key questions include whether vitamin C improves aging-related indicators and the safety of taking vitamin C supplements. Participants will be randomly assigned to take either vitamin C tablets 500 mg twice daily or placebo tablets with the same appearance, twice a day after breakfast and dinner for 12 months. A baseline control group of healthy volunteers aged 18 to 70 will not receive any intervention but will be observed for age-related changes. Participants will attend face-to-face follow-ups every 6 months and telephone check-ins every 2 months to report medication use and any adverse effects. They will complete health questionnaires and undergo comprehensive health exams, including blood tests, at 6 and 12 months. Researchers will evaluate aging intervention effectiveness, cognitive and physical function, muscle mass, cardiovascular health, vitamin C levels, and various biological markers over the year.

Exploratory Study on the Role of Vitamin C in Promoting Health in Middle-Aged and Elderly Adults