Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07114770

Explore the Impacts of One Session and Multiple Session Theta Burst Stimulation Over Cerebellum in Adults With Autism Spectrum Disorder

Led by Chang Gung Memorial Hospital · Updated on 2025-08-11

60

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

Sponsors

C

Chang Gung Memorial Hospital

Lead Sponsor

N

National Health Research Institutes, Taiwan

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to establish a personalized theta burst stimulation (TBS, an advanced variant of repetitive transcranial magnetic stimulation, rTMS) protocol considering autistic idiosyncrasy (interindividual variability).

CONDITIONS

Official Title

Explore the Impacts of One Session and Multiple Session Theta Burst Stimulation Over Cerebellum in Adults With Autism Spectrum Disorder

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older with autism spectrum disorder confirmed by Autism Diagnostic Observation Schedule
  • Autism Spectrum Disorder severity level 1 or 2 according to DSM-5
  • Adults aged 18 years or older without autism spectrum disorder for typically developing control group
Not Eligible

You will not qualify if you...

  • Previous or current severe neurological disorders including epilepsy
  • Severe systemic diseases such as cardiovascular disease, diabetes, or hypertension
  • Previous or current severe brain injury
  • Presence of metal implants such as pacemakers or medication pumps
  • Severe psychiatric disorders including schizophrenia, bipolar disorder, severe major depressive disorder, or substance abuse
  • Pregnancy
  • Intracranial space occupying lesions
  • Previous brain surgery or central nervous system infection
  • Use of medications that increase seizure risk
  • Participation in another clinical trial within one month
  • Damaged skin at the stimulation site
  • Multiple sclerosis
  • Large ischemic scars
  • History of sleep disorders during brain stimulation
  • Severe alcoholism
  • Use of antiepileptic drugs
  • Uncontrollable migraines due to increased intracranial pressure
  • Unsuitable for MRI (e.g., claustrophobia)
  • Unsuitable for EEG
  • Autism Spectrum Disorder severity level 3 according to DSM-5
  • Suicidal ideation within one year

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chang Gung Memorial Hospital

Taoyuan, Taiwan

Actively Recruiting

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Research Team

H

Hsing-Chang Ni, Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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