Actively Recruiting
Explore the Impacts of Theta Burst Stimulation Over the Right Inferior Frontal Gyrus in Autism Spectrum Disorder: Combination of Clinical Symptoms, Neuropsychological Function and MRI
Led by Chang Gung Memorial Hospital · Updated on 2026-05-12
60
Participants Needed
1
Research Sites
243 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Exploring the therapeutic efficacy of Theta Burst Stimulation (TBS) over the right inferior frontal gyrus (RIFG) in autism, including changes in core symptoms, adaptive functioning, neuropsychological performance, and neurophysiological signals.
CONDITIONS
Official Title
Explore the Impacts of Theta Burst Stimulation Over the Right Inferior Frontal Gyrus in Autism Spectrum Disorder: Combination of Clinical Symptoms, Neuropsychological Function and MRI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 8 to 30 years
- Clinical diagnosis of Autism Spectrum Disorder confirmed by ADOS-2
- DSM-5 severity level of ASD: level 1 or level 2
- Stable treatment regimen prior to study or assessed as ineffective conventional treatments or declined conventional treatment
- Score of �3e= 15 on the University of California Brief Assessment of Capacity to Consent (UBACC) and understanding of study aims and risks
You will not qualify if you...
- Severe neurological disorders such as epilepsy, visual or auditory impairments
- Severe systemic diseases like cardiovascular disease, diabetes, or hypertension
- Severe brain injury
- Metal implants such as pacemaker or medication pump
- Severe psychiatric disorders including schizophrenia, bipolar disorder, or substance abuse
- Pregnancy
- Significant brain abnormalities, including intracranial space-occupying lesions
- Previous brain surgery or central nervous system infection
- Use of medications increasing seizure risk
- Participation in another clinical trial within one month
- Damaged skin at stimulation site
- Multiple sclerosis
- Large ischemic scars
- Sleep disorders during brain stimulation
- Severe alcoholism
- Use of antiepileptic drugs
- Uncontrollable migraines due to increased intracranial pressure
- Unsuitable for MRI (e.g., claustrophobia)
- Unsuitable for EEG
- DSM-5 severity level of ASD: level 3
- Current major depressive disorder
- Suicidal thoughts within one year
- Currently taking tricyclic antidepressants, analgesics, or medications lowering seizure threshold
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Chang Gung Memorial Hospital
Taoyuan, Taiwan
Actively Recruiting
Research Team
H
Hsing-Chang Ni, Ph.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here