Actively Recruiting
Exploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma
Led by Zhongnan Hospital · Updated on 2025-05-28
100
Participants Needed
1
Research Sites
224 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this prospective study, the investigators will use integrated PET/CT with the agent 68Ga-FAPI and conventional imaging agent 18F-FDG to explore the application value of FAP-targeted molecular imaging in the diagnosis and staging for oral cancer. This study also aims to explore the application value of FAPI imaging in evaluating treatment response for oral cancer.
CONDITIONS
Official Title
Exploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntary participation with signed informed consent
- Aged 18 to 70 years
- Clinically highly suspected oral cancer or recurrence after treatment
- Newly diagnosed patients scheduled for surgery or neoadjuvant therapy followed by surgery
- Ability to complete baseline and follow-up PET/CT scans (follow-up applies for locally advanced patients receiving neoadjuvant therapy)
You will not qualify if you...
- Pregnant or breastfeeding women, or planning pregnancy during the trial
- Known allergy or severe reaction to FAPI, FDG, or their components
- Poor general health with heart, lung, liver, kidney, or other vital organ dysfunction preventing surgery
- Fasting blood glucose level above 11.0 mmol/L before 18F-FDG injection
- Claustrophobia or inability to lie still and tolerate PET/CT imaging for 15 to 30 minutes
- Participation in another interventional clinical trial within 30 days before enrollment or planned during this study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zhongnan Hopital of Wuhan University
Wuhan, Hubei, China, 430071
Actively Recruiting
Research Team
J
Jiang Yaqun, PhD
CONTACT
H
He Yong, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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