Actively Recruiting

Early Phase 1
Age: 18Years - 75Years
All Genders
NCT07505069

Exploring the Clinical Value of RT01-89Zr PET Imaging in Solid Tumors

Led by Nanolattix Biotechnology Co., Ltd. · Updated on 2026-04-01

10

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

RT01-89Zr is a TF-targeting radiopharmaceutical diagnostic agent. This trial aims to evaluate the safety, biodistribution, dosimetry, and imaging characteristics of RT01-89Zr as a PET/CT tracer in patients with malignant solid tumors that highly express the TF target.

CONDITIONS

Official Title

Exploring the Clinical Value of RT01-89Zr PET Imaging in Solid Tumors

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of either gender, ages 18-75 (including 18 and 75)
  • ECOG Performance Status of 0 or 1
  • Confirmed solid tumor diagnosis by histopathology or cytology
  • At least one primary or metastatic lesion confirmed by imaging
  • Availability of tumor tissue samples showing more than 1% target expression
  • Willingness to participate, sign informed consent, and comply with study procedures
  • Women of childbearing potential must have a negative pregnancy test and agree to use effective contraception until 3 months after drug administration
Not Eligible

You will not qualify if you...

  • Unable to complete a PET/CT scan (e.g., cannot lie flat, claustrophobia, fear of radiation)
  • Received radiopharmaceuticals recently without sufficient discontinuation period
  • Participation in other clinical trials within the past 3 months or plans to participate during the study
  • Presence of acute systemic diseases or electrolyte disorders
  • Known allergy to RT01 contrast agent or its components
  • Poor adherence as judged by researchers
  • Pregnant or breastfeeding
  • Other factors making participation unsuitable as determined by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Affiliated Hospital of Jiangnan University

Wuxi, Jiangsu, China, 214122

Actively Recruiting

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Research Team

J

Jingchun Yu

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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