Actively Recruiting
Exploring the Effects of Exercise on Memory and Cognition in Parkinson´s Disease
Led by Heidelberg University · Updated on 2024-08-30
60
Participants Needed
1
Research Sites
174 weeks
Total Duration
On this page
Sponsors
H
Heidelberg University
Lead Sponsor
G
German Foundation for Neurology
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study aims to assess the effects of cardiovascular (aerobic) training on memory formation and cognitive function in people with Parkinson's disease. Participants will be randomly allocated to one of two groups either performing cardiovascular training (experimental group) or stretching (control group) for twelve weeks, three times a week. The primary aim is to examine whether moderate-intense cardiovascular training (MICT) improves procedural memory formation (primary outcome) compared to stretching. Secondary outcomes include episodic memory formation, cognitive function, cardiorespiratory fitness, sleep quality, and brain-derived neurotrophic factor (BDNF) blood concentration levels.
CONDITIONS
Official Title
Exploring the Effects of Exercise on Memory and Cognition in Parkinson´s Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed Parkinson's disease
- Parkinson's disease stage 3 or lower on the Hoehn & Yahr scale
- Age between 50 and 80 years
- No prior experience with the memory tasks used in the study
- Ability to stand and walk independently for at least 10 meters
You will not qualify if you...
- Atypical Parkinsonism
- Significant cognitive impairment (Montreal Cognitive Assessment score less than 21)
- Having deep brain stimulation or a brain pacemaker
- Diagnosed psychiatric illness
- Other neurological, internal, or orthopedic conditions that would interfere with exercise
- Exceeding recommended cardiovascular exercise levels (more than 150 minutes moderate or 75 minutes vigorous per week)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Heidelberg University
Heidelberg, Baden-Wurttemberg, Germany, 69120
Actively Recruiting
Research Team
S
Simon Steib, Prof. Dr.
CONTACT
P
Philipp Wanner, Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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