Actively Recruiting
Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD
Led by Far Eastern Memorial Hospital · Updated on 2026-03-20
60
Participants Needed
2
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a longitudinal, multicenter, single-blind, two-arm randomized controlled trial designed to evaluate the effectiveness of Multi-Modal Cognitive Processing Therapy (MMCPT) for individuals with posttraumatic stress disorder (PTSD). Participants will be randomly assigned to either the intervention group receiving MMCPT or a control group receiving treatment-as-usual (TAU). The intervention follows the standard CPT manual developed by Resick and consists of twelve weekly 90-minute individual sessions. The primary outcomes include PTSD symptom severity assessed by the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Checklist for DSM-5 (PCL-5). Secondary outcomes include sleep quality (actigraphy, PSQI), anxiety (STAI), depression (HDRS-17), remission rate, and posttraumatic growth (PTGI). Assessments will occur at baseline, mid-treatment, post-treatment, and at 3-, 6-, 9-, and 12-month follow-ups.
CONDITIONS
Official Title
Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 20 and 65 years
- Diagnosed with PTSD according to DSM-5 criteria
- Score 233 on the PTSD Checklist for DSM-5 (PCL-5)
- Able to provide informed consent
- Stable psychiatric medication regimen (if any) for at least 4 weeks prior to enrollment
You will not qualify if you...
- Diagnosed with schizophrenia, schizoaffective disorder, or bipolar I disorder
- Current substance dependence or abuse within the past 6 months
- Severe suicidal ideation or suicide attempt in the past 6 months
- Cognitive impairment or neurological disorder affecting participation
- Concurrent participation in other psychological treatment for PTSD
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Far Eastern Memorial Hospital
New Taipei City, Banqiao District, Taiwan, 220
Not Yet Recruiting
2
Far Eastern Memorial Hospital
New Taipei City, Banqiao District, Taiwan, 220
Actively Recruiting
Research Team
H
Hsin-I Liu, PhD, RN
CONTACT
P
Pei-Chuan Wu, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here