Actively Recruiting

Phase Not Applicable
Age: 4Years - 15Years
All Genders
NCT06677840

Exploring the Gut-Brain-Behavior Axis With Biomarkers, Probiotic Efficacy, and Artificial Intelligence Algorithms

Led by National Taiwan University Hospital · Updated on 2024-11-07

110

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This groundbreaking human study on the ASD microbiome includes probiotic clinical trials, investigation of treatment biomarkers, machine learning/deep learning platform development for ASD classification and prediction, and identification of diagnostic biomarkers. Upon completion, the investigators anticipate publishing at least 12 SCI papers and/or patents and establishing an auxiliary diagnosis platform for both clinical and academic purposes. The findings will offer new insights into the pathogenetic mechanisms, improving early detection, diagnosis, and treatment, ultimately advancing precision medicine for ASD.

CONDITIONS

Official Title

Exploring the Gut-Brain-Behavior Axis With Biomarkers, Probiotic Efficacy, and Artificial Intelligence Algorithms

Who Can Participate

Age: 4Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children and adolescents aged 4 to 15 who are clinically diagnosed with ASD according to DSM-5 criteria and confirmed by the ADI-R/ADOS.
  • Caregivers cooperate with all the assessments and stool and blood collection.
Not Eligible

You will not qualify if you...

  • History of major psychiatric disorders such as schizophrenia, bipolar disorder, or major depression.
  • History of neurological disorders.
  • History of substance use disorders.
  • Difficulty following instructions.
  • Use of antibiotics, yogurt, or probiotic products within two weeks prior to enrollment.

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan

Actively Recruiting

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Research Team

S

Susan Shur-Fen Gau, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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