Actively Recruiting
Exploring How Viral Infections Affect People With Chronic Lung Disease
Led by Imperial College London · Updated on 2025-07-14
180
Participants Needed
1
Research Sites
125 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Many people with chronic lung disease have disease flare-ups. It was previously believed that these were mainly caused by bacteria but recent evidence suggests that viruses could be an important trigger. This study will recruit volunteers with chronic lung disease and take samples both when well (at baseline) and during flare-ups (exacerbations) to better understand the role of viruses in triggering exacerbations and also how the immune response is affected. The researchers will follow the volunteers\' progress for up to two years. Whenever they get unwell they will take some samples (nose swabs, finger prick testing, phlegm sample) and post them to the researchers. Then, they will come in for a visit for more samples (blood tests, further swabs) and a review.
CONDITIONS
Official Title
Exploring How Viral Infections Affect People With Chronic Lung Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults with a physician confirmed diagnosis of chronic airway disease such as COPD or bronchiectasis according to established criteria
- Prior history of exacerbation within the last year requiring antibiotics and/or corticosteroids
You will not qualify if you...
- Unable to complete daily symptom diaries or attend clinical assessments
- Exacerbation within 4 weeks before study recruitment or clinical instability at recruitment
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Royal Brompton Hospital
London, United Kingdom
Actively Recruiting
Research Team
P
Patrick Senior
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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