Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT04171856

Exploring Motor Learning in Acute Stroke Through Robotics

Led by University Hospital of Mont-Godinne · Updated on 2025-04-03

245

Participants Needed

2

Research Sites

1069 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The acute phase of stroke is characterized by an enhancement of neural plasticity which supports rapid motor recovery. It is unclear whether acute stroke patients can acquire new motor skills with their affected upper limb. The aims of this research program are: 1. To test the capacity of acute stroke patients (\< 21 days) to learn and retain a complex unimanual motor skill. 2. To explore whether acute stroke to different brain regions (quantified with brain MRI) induces specific deficits in motor skill learning. 3. To compare acute stroke patients with healthy individuals and with chronic stroke patients.

CONDITIONS

Official Title

Exploring Motor Learning in Acute Stroke Through Robotics

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Acute stroke within 21 days
  • Age between 18 and 90 years
  • Stroke lesion visible on brain imaging
  • For transient global amnesia patients: clinical diagnosis per Hodge & Warlow criteria, ability to perform 3 sessions on rehabilitation robot, age 8 to 90 years
  • Healthy individuals aged 18 to 90 years
  • Chronic stroke patients with stroke more than 6 months ago, aged 18 to 90 years, with stroke lesion on brain imaging
Not Eligible

You will not qualify if you...

  • Contraindications to MRI such as non-MR-compatible pacemaker or implanted devices, pregnancy, or claustrophobia
  • Difficulty understanding or following commands
  • Drug or alcohol abuse
  • Severe aphasia or cognitive deficits interfering with the study
  • Inability to voluntarily move the affected arm (complete paralysis)
  • Multiple strokes, dementia, or psychiatric conditions
  • For transient global amnesia patients: psychiatric disorders, alcohol or drug addiction, and MRI contraindications
  • Healthy individuals with medical history of stroke or neurological deficits
  • Chronic stroke patients with the above exclusions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

CHU UCL Namur

Yvoir, Namur, Belgium, 5530

Actively Recruiting

2

University Hospital CHU Dinant Godinne UCL

Yvoir, Belgium, 5530

Not Yet Recruiting

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Research Team

Y

Yves Vandermeeren, MD, PhD

CONTACT

E

Eloïse Gerardin, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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