Actively Recruiting
Exploring the Neo-Adjuvant Therapy Effects on Lung Cancer Through Monitoring and Assessment of Tumor Environment
Led by Shanghai Pulmonary Hospital, Shanghai, China · Updated on 2023-06-08
2000
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This translational study aims to investigate how neoadjuvant therapy affects lung cancer patients by monitoring dynamic changes in the tumor environment. The study focuses on patients with histologically confirmed lung cancer, including non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), who are eligible for neoadjuvant therapy in the LungMate clinical trial series. By analyzing intra-tumour genetic and functional heterogeneity following neoadjuvant therapy through multi-omic analysis (including genomics, transcriptomics, metabolomics and proteomics), this study could potentially identify new biomarkers or therapeutic targets that could improve lung cancer patient outcomes.
CONDITIONS
Official Title
Exploring the Neo-Adjuvant Therapy Effects on Lung Cancer Through Monitoring and Assessment of Tumor Environment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients enrolled in LungMate clinical trial series, including LungMate-001 through LungMate-015 and future LungMate neoadjuvant therapy lung cancer trials
- Age 18 years or older
- Histologically confirmed diagnosis of non-small cell lung cancer or small cell lung cancer
- Written informed consent provided
You will not qualify if you...
- Patients who do not meet clinical trial screening criteria or who dropped out of the clinical trial
- Any condition that makes participation undesirable or risks protocol compliance, as judged by the investigator
- History of other cancers within 5 years before the trial, except cervical carcinoma in situ, cured basal cell carcinoma, and bladder epithelial tumors (including Ta and Tis)
- Carrier of active hepatitis B, hepatitis C, or HIV infection
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Pulmonary Hospital
Shanghai, China, 200433
Actively Recruiting
Research Team
P
Peng Zhang, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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