Actively Recruiting
Hypercalcemia After Cosmetic Paraffin Oil Injections: Unravelling Etiology, Pathogenesis and Potential Treatments
Led by Herlev Hospital · Updated on 2024-10-01
200
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying hypercalcemia and related conditions caused by cosmetic intramuscular injections of paraffin oil. The study aims to understand the cause, development, and natural history of paraffin oil-induced granulomatous disease, called paraffin disease. The goal is to discover new treatments through translational research that can be tested in future clinical trials. This is an observational study without treatment intervention, focusing on patients who have previously received intramuscular injections of paraffin or other oils. The study does not include any experimental drug or device administration but monitors patients over time to gather data on disease progression and biological markers. Participants will undergo examinations to measure ionized calcium and parathyroid hormone (PTH) levels in plasma. Researchers will track these markers at the first visit and throughout an observation period extending up to 2025. The study is designed to better understand disease mechanisms and potential treatment targets, with no interventional procedures involved. The total study period extends until early 2027.
CONDITIONS
Brief Title
Exploring Pathogenesis and Treatment of Hypercalcemia Caused by Intramuscular Injection of Paraffinoil
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Previous intramuscular injection of paraffin or other oil
- Age 18 years or older
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 4 years until January 2027
Participants are observed over time to monitor calcium and parathyroid hormone levels after previous intramuscular paraffin or oil injections.
Periodic visits for assessments until 2027
Trial Site Locations
Total: 1 location
1
Herlev Hospital
Copenhagen, Denmark
Actively Recruiting
Research Team
E
Ebbe Eldrup, DMSc
M
Martin Blomberg Jensen, DMSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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