Actively Recruiting
Exploring Prolonged Arthrogenic Muscle Responses and Associated Factors After Anterior Cruciate Ligament Reconstruction
Led by University Ghent · Updated on 2024-07-01
190
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University Ghent
Lead Sponsor
R
Research Foundation Flanders
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are exploring the long-term presence of arthrogenic muscle responses (AMR) in patients who have undergone anterior cruciate ligament (ACL) reconstruction. This observational study aims to understand how factors like fear of movement (kinesiophobia), subjective knee function and stability, pain levels, and clinical parameters relate to prolonged AMR occurrence. The study is sponsored by University Ghent and focuses on adults aged 18 to 40 who have had ACL surgery. Participants will complete questionnaires one week before surgery and at one and three months after surgery. These questionnaires collect demographic information and assess knee function, activity levels, pain during day and night, and readiness to return to sport. At five months post-surgery, participants will undergo a testing protocol that includes electromyographical measurements of hamstrings and quadriceps during jumping tasks and assessments of quadriceps inhibition to evaluate prolonged AMR. During the study, researchers will measure voluntary quadriceps activation and muscle activity during jumping tasks at five months after surgery. Secondary outcomes include quadriceps and hamstrings strength as well as patient-reported knee function at the same time point. Participants will be closely monitored through questionnaires and muscle testing to gather comprehensive data on recovery and muscle response after ACL reconstruction.
CONDITIONS
Brief Title
Exploring Prolonged AMR in ACL Reconstructed Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 18 and 40 years old
- Have suffered an ACL rupture
- Be scheduled for surgical ACL reconstruction at the AZ Delta hospital in Roeselare (Campus Brugsesteenweg)
You will not qualify if you...
- Have had a revision ACL reconstruction
- Have had other severe lower limb injuries within the past year
- Have muscular or neurological disorders affecting lower limb function
- Have fibromyalgia or chronic fatigue syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of surgery
Participants undergo anterior cruciate ligament reconstruction surgery as scheduled.
1 visit (in-person)
Duration - Up to 5 months post ACL reconstruction
Participants are observed and assessed for muscle responses and knee function after surgery.
Assessments at approximately 5 months post ACL reconstruction
Trial Site Locations
Total: 1 location
1
AZ Delta Hospital (Campus Brugsesteenweg)
Roeselare, West-Vlaanderen, Belgium, 8800
Actively Recruiting
Research Team
E
Erik Witvrouw, prof. dr.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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