Actively Recruiting

Age: 18Years - 65Years
All Genders
Healthy Volunteers
ID06964100

Exploring the Relationship Between Heart Rate Variability, Training Load, and Endurance Performance

Led by PepsiCo Global R&D · Updated on 2025-05-09

200

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how heart rate variability (HRV), training load, and endurance performance relate to each other in real-world settings. The study aims to test user engagement, app functionality, and feasibility of the new Gatorade Sports Science Institute (GSSI) Labs App to conduct remote research. It also seeks to explore whether training intensity during low HRV periods affects 5K running times, potentially leading to personalized training using HRV data. Participants will use wearable activity trackers to collect data such as physical activity, heart rate, and other exercise metrics. They will perform self-timed 5K runs at baseline (Week 1), mid-study (Week 4), and after eight weeks (Week 8), using the same course or treadmill to maintain consistency. The study is fully remote with no in-person visits, relying on the GSSI Labs App for data collection. During the study, participants will continuously wear their activity trackers, including during sleep, except when underwater. Researchers will monitor app engagement from activation through Week 8 and collect biometric data like HRV, resting heart rate, sleep quantity, sleep efficiency, sleep consistency, and training zone percentages at the three 5K timepoints. The study lasts eight weeks, and all assessments are done remotely via the app and wearable devices.

CONDITIONS

Brief Title

Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Endurance Performance

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Actively participating in cardiovascular training 3 to 5 days per week
  • Able to run a 5K distance three times over eight weeks at a self-selected location
  • Age between 18 and 65 years
  • Willing to avoid vigorous exercise 24 hours before each timed 5K run
  • Willing to avoid alcohol consumption 24 hours before each timed 5K run
  • Able and willing to provide consent
  • Able to continuously wear a compatible activity tracker, including during sleep except underwater
  • Owns a compatible wearable device such as Android, Apple Health, Dexcom, Fitbit, Garmin, Health Connect, Oura, Polar, Whoop, or Withings
Not Eligible

You will not qualify if you...

  • Has a condition that interferes with informed consent, study compliance, or could affect study results or safety
  • Medical history that would interfere with study results
  • One or more cardiovascular disease risk factors per American College of Sports Medicine
  • Men aged 45 years or older; women aged 55 years or older
  • Family history of early heart attack, bypass surgery, or sudden death before age 55 (men) or 65 (women)
  • Current smoker, quit less than 6 months ago, or exposed to environmental smoke
  • Sedentary lifestyle, defined as less than moderate physical activity at least 3 days/week for 3 months
  • Obesity: BMI 30 kg/m2 or higher, or waist circumference 102 cm (40 inches) or more for men and 88 cm (35 inches) or more for women
  • Hypertension: blood pressure 140/90 mmHg or higher, or taking medication
  • Dyslipidemia: LDL 130 mg/dl or higher, HDL less than 40 mg/dl, triglycerides over 200 mg/dl, or taking medication
  • Pre-diabetes based on fasting glucose or oral glucose tolerance test
  • Under medical care
  • Sleep disorders or taking prescription medications affecting sleep
  • Pregnant, planning pregnancy, or breastfeeding
  • Unable to continuously wear activity tracker
  • Lack of proficiency in English
  • Lack of internet access or email
  • Participation in another clinical trial within past 30 days
  • Employed by or immediate family employed by a company competing with Gatorade products

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or virtual) for eligibility assessment and consent

Monitoring

Duration - 8 weeks

Participants continuously wear a compatible activity tracker to record physiological and subjective health measures including heart rate variability, resting heart rate, and sleep metrics while performing self-administered 5K timed runs at Weeks 1, 4, and 8.

3 self-administered 5K runs during Week 1, Week 4, and Week 8

Trial Site Locations

Total: 1 location

1

Remote study, no physical site. Managed by Gatorade Sports Science Institute. Do not contact investigators to enroll. Recruitment is handled by an independent agency.

Chicago, Illinois, United States, 60607

Actively Recruiting

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Research Team

C

Corey Ungaro, do not contact to enroll, PhD

E

Eric Freese, do not contact to enroll, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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