Actively Recruiting

Phase 1
Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT06999434

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

Led by Yale University · Updated on 2025-05-31

105

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

N

National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The overall objective is to obtain an assessment of the pharmacokinetics of \[18F\]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple Sclerosis (MS), Spinal Cord Injury (SCI) and Spinal radiculopathy (SR).

CONDITIONS

Official Title

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female subjects aged 18 to less than 90 years
  • Able to understand and provide informed consent before study procedures
  • Must be in good health
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Pregnant or breastfeeding
  • Any significant systemic illness or unstable medical condition
  • Pre-existing medical conditions or claustrophobic reactions
  • Research-related radiation exposure exceeding 50 mSv in the prior 12 months
  • History of bleeding disorders or currently taking anticoagulants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Yale University PET Center

New Haven, Connecticut, United States, 06510

Actively Recruiting

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Research Team

S

Shannan Henry

CONTACT

K

Kayla Cottiers

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

6

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Exploring the Utility of [18F]3F4AP for Demyelination Imaging | DecenTrialz