Actively Recruiting
Exploring the Value of Urine Proteomics-based Dynamic Surveillance for Early Recurrence After Radical Surgery for Hepatocellular Carcinoma: a Prospective Cohort Study
Led by Zhujiang Hospital · Updated on 2025-03-06
38
Participants Needed
1
Research Sites
149 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, we explored and validated the predictive value of the longitudinal monitoring model of urinary proteomics for postoperative recurrence of hepatocellular carcinoma and the predictive value of minimal residual disease (MRD) status, verified whether it is earlier than the recurrence suggested by imaging tests, and initially explored its clinical feasibility in guiding the adjuvant treatment of hepatocellular carcinoma in the postoperative period, so as to provide a new idea for the strategy of early intervention in the postoperative period of hepatocellular carcinoma.
CONDITIONS
Official Title
Exploring the Value of Urine Proteomics-based Dynamic Surveillance for Early Recurrence After Radical Surgery for Hepatocellular Carcinoma: a Prospective Cohort Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with hepatocellular carcinoma whose tumor stage at initial diagnosis is BCLC 0, stage A, or stage B
- Patients able to undergo radical surgical resection
- Patients who have not received any anti-tumor therapy before surgery
You will not qualify if you...
- Unable to provide urine samples for proteomics testing
- History of renal or urologic disease
- Having two or more tumors at the same time
- Presence of non-primary liver disease
- Previous treatment with anti-tumor therapies such as targeted immunotherapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhujiang Hospital of Southern Medical University
Guangzhou, Guangdong, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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