Actively Recruiting

Phase 4
Age: 1Day - 23Months
All Genders
NCT02096536

Exploring Vancomycin Disposition in Neonates

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-12

120

Participants Needed

1

Research Sites

561 weeks

Total Duration

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AI-Summary

What this Trial Is About

Vancomycin is already used for decades in neonates. However, there are remaining questions concerning vancomycin disposition in this population. The purpose of this study is first of all to perform a paired analysis of serum vancomycin concentrations using an immunoassay versus a reference liquid chromatography-tandem mass spectrometry method. Secondly, we aim to determine vancomycin protein binding and its covariates in neonates.

CONDITIONS

Official Title

Exploring Vancomycin Disposition in Neonates

Who Can Participate

Age: 1Day - 23Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Neonates admitted to the Neonatal Intensive Care Unit who are receiving vancomycin treatment by medical decision
  • Informed consent given by parents
Not Eligible

You will not qualify if you...

  • Not receiving vancomycin therapy
  • No signed informed consent available

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UZ Leuven

Leuven, Vlaams-Brabant, Belgium, 3000

Actively Recruiting

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Research Team

A

Anne Smits, MD

CONTACT

K

Karel Allegaert, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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