Actively Recruiting

Phase Not Applicable
Age: 18Years - 59Years
All Genders
Healthy Volunteers
NCT07018128

Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure

Led by Burapha University · Updated on 2026-05-11

200

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study consists of two sub-studies. Study 1 investigates gene expression related to the development of hypertension in Thailand, and Study 2 examines the effectiveness of the 4-7-8 breathing technique in reducing blood pressure in individuals with hypertension.

CONDITIONS

Official Title

Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure

Who Can Participate

Age: 18Years - 59Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged between 18 and 59 years
  • Of Thai ethnicity
  • Originally from various regions of Thailand and currently residing in the eastern region
  • For hypertensive group: diagnosed with hypertension (SBP ≥ 140 mmHg, or DBP ≥ 90 mmHg) or taking antihypertensive medication
  • For normal blood pressure group: SBP below 130 mmHg and DBP below 85 mmHg, no prior hypertension diagnosis or medication
  • For Study 2: aged 35-59 years, diagnosed with hypertension (SBP ≥ 130 mmHg or DBP ≥ 85 mmHg) and currently taking medication
  • Able to communicate effectively
Not Eligible

You will not qualify if you...

  • Heart disease such as valvular stenosis or regurgitation, coronary artery disease, or heart failure
  • Obesity with BMI of 30 kg/m² or higher
  • Fever or current infectious disease such as COVID-19, flu, or others
  • Respiratory diseases, cardiovascular diseases, cerebrovascular disease, kidney disease, cancer, or immune-related conditions including allergies, autoimmune diseases, immunodeficiency, or rheumatoid arthritis (for Study 2)
  • Currently pregnant, breastfeeding, or history of pregnancy within 6 months prior to study (for Study 2)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Allied Health Sciences, Burapha University

MueangChonburi, Changwat Chon Buri, Thailand, 20131

Actively Recruiting

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Research Team

P

Piyapong Prasertsri, Ph.D.

CONTACT

T

Tadsawiya Padkao, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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