Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
MALE
Healthy Volunteers
NCT05558345

Expression of Stress Markers During Meth Treatment (EXPRESS+)

Led by University of California, Los Angeles · Updated on 2024-05-07

55

Participants Needed

1

Research Sites

186 weeks

Total Duration

On this page

Sponsors

U

University of California, Los Angeles

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a non-randomized behavioral trial that aims to investigate whether changes in inflammatory and type I IFN expression coincide with changes in methamphetamine use and viral load over the course of 12 weeks in HIV-positive people assigned male at birth with and without methamphetamine use disorder.

CONDITIONS

Official Title

Expression of Stress Markers During Meth Treatment (EXPRESS+)

Who Can Participate

Age: 18Years - 45Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Assigned male sex at birth
  • Aged 18 to 45 years
  • Reports having sex with men in the past 12 months
  • HIV-positive (confirmed by certification or rapid test)
  • Has an HIV care provider seen in the past 12 months
  • Has a current antiretroviral prescription
  • For methamphetamine use disorder group: meets DSM-5 criteria for methamphetamine use disorder using SCID-5
  • For methamphetamine use disorder group: urine test positive for methamphetamine within 30 days of screening
  • For methamphetamine use disorder group: seeking treatment for methamphetamine use disorder
  • For methamphetamine use disorder group: able to attend twice weekly appointments for drug testing and treatment
Not Eligible

You will not qualify if you...

  • Identifies as (cis- or transgender) female
  • For methamphetamine use disorder group: reports another current or past substance use disorder
  • For methamphetamine use disorder group: currently in another intervention or clinical trial for substance use
  • For methamphetamine use disorder group: positive test for opioids, cocaine, and/or MDMA
  • For control group: positive test for methamphetamine, opioids, cocaine, and/or MDMA
  • For control group: reports substance use (methamphetamine, opioids, cocaine, MDMA, hallucinogens, heavy alcohol use, and/or tobacco) in the past 6 months
  • For control group: reports past or current substance use disorder

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UCLA Vine Street Clinic

Los Angeles, California, United States, 90038

Actively Recruiting

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Research Team

M

Michael J Li, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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