Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06493227

Extended Perioperative Administration of Fibrinolysis Inhibitors After Cardiac Surgery

Led by Saint Petersburg State University, Russia · Updated on 2025-01-27

1373

Participants Needed

2

Research Sites

95 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

PRIORITY is a pragmatic, multi-center, cluster crossover trial that aims to evaluate whether implementing a policy of routine extended (intraoperative and 4 hour after transfer to ICU) use of fibrinolysis inhibitors leads to a decrease in post-operative blood transfusion compared to a policy that only involves intraoperative use.

CONDITIONS

Official Title

Extended Perioperative Administration of Fibrinolysis Inhibitors After Cardiac Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospital performs at least 250 open heart surgeries per year
  • More than 95% of hospital physicians treating adult patients (over 18 years) agree to follow the study's fibrinolysis inhibitor use protocol
Not Eligible

You will not qualify if you...

  • Hospital does not meet the inclusion criteria

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Cardiac surgery department, Saint-Petersburg state university hospital

Saint Petersburg, Russia

Actively Recruiting

2

St. Petersburg State University Hospital

Saint Petersburg, Russia

Not Yet Recruiting

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Research Team

S

Sergey Efremov, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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