Actively Recruiting
Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2023-06-08
126
Participants Needed
16
Research Sites
303 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
M
Ministry of Health, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is a randomized trial that evaluates the effect of metformin addition or not to standard care on the duration of diabetes remission after bariatric surgery.
CONDITIONS
Official Title
Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18-70 years old
- Had gastric bypass or sleeve gastrectomy 12 to 36 ±3 months before joining
- Had type 2 diabetes treated with at least one anti-diabetic drug before surgery or HbA1c ≥ 6.5% before surgery
- Have HbA1c less than 6.5% at inclusion with no diabetes medications for the last three months
- Provided written consent
You will not qualify if you...
- Known type 1 diabetes
- Pregnant or breastfeeding
- Estimated kidney function (glomerular filtration rate) below 44 ml/min
- Known intolerance or contraindications to metformin, including acute metabolic acidosis, conditions causing kidney problems, severe heart or lung diseases, recent heart attack, liver failure, very low prothrombin ratio, very high liver enzymes, or alcohol use disorder
- Taking medications or having medical conditions that interfere with diabetes assessment such as glucocorticoid treatment, kidney transplant, Cushing's syndrome, acromegaly, or very high triglycerides despite treatment
- Under legal protection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 16 locations
1
CHU Amiens-Picardie - hôpital Nord
Amiens, France
Actively Recruiting
2
AP-HP - hôpital Avicenne
Bobigny, France
Withdrawn
3
CHU de Bordeaux - hôpital Haut-Lévêque
Bordeaux, France
Actively Recruiting
4
AP-HP - hôpital Ambroise-Paré
Boulogne-Billancourt, France
Actively Recruiting
5
AP-HP - hôpital Louis-Mourier
Colombes, France
Actively Recruiting
6
Centre hospitalier intercommunal de Créteil
Créteil, France
Actively Recruiting
7
CHU de Lille - hôpital Claude Huriez
Lille, France
Actively Recruiting
8
AP-HM - hôpital de la Conception
Marseille, France
Actively Recruiting
9
AP-HM - hôpital Nord
Marseille, France
Withdrawn
10
AP-HP - hôpital européen Georges-Pompidou
Paris, France, 75015
Actively Recruiting
11
AP-HP - hôpital Bichat-Claude Bernard
Paris, France
Actively Recruiting
12
AP-HP - hôpital de la Pitié-Salpêtrière
Paris, France
Actively Recruiting
13
Institut Mutualiste Montsouris
Paris, France
Actively Recruiting
14
HCL - centre hospitalier Lyon-Sud
Pierre-Bénite, France
Actively Recruiting
15
CH de Saint-Denis - hôpital Delafontaire
Saint-Denis, France
Not Yet Recruiting
16
CHU de Toulouse - hôpital Larrey
Toulouse, France
Actively Recruiting
Research Team
A
Aurélie GUIMFACK
CONTACT
Y
Yvann FRIGOUT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here