Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT07233083

External Oblique Intercostal Plane Block for Liver Transplantation Recipient

Led by Istinye University · Updated on 2026-01-08

60

Participants Needed

1

Research Sites

23 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Postoperative pain management is one of the key factors in improving rehabilitation and accelerating recovery. The external oblique intercostal plane block can be used to provide abdominal wall analgesia for effective pain control in abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of the external oblique intercostal plane block in liver transplant recipients. The investigators will compare a group receiving the external oblique intercostal plane block with a control group to determine whether this block provides effective postoperative analgesia in liver transplant recipients.

CONDITIONS

Official Title

External Oblique Intercostal Plane Block for Liver Transplantation Recipient

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 to 75 years
  • Scheduled for elective orthotopic liver transplantation (living or deceased donor)
  • Planned J-shaped or Mercedes incision
  • ASA physical status III-IV
  • Normal or acceptable coagulation profile at block application (INR ≤ 1.5, platelet count ≥ 50,000/mm³, fibrinogen ≥ 150 mg/dL)
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Coagulopathy at block application (INR > 1.5, platelet count < 50,000/mm³, or fibrinogen < 150 mg/dL)
  • Known allergy or hypersensitivity to local anesthetics (amide group)
  • Local infection or skin lesion at block injection site
  • Severe hemodynamic instability requiring high-dose vasopressor support
  • Chronic opioid use (≥30 mg oral morphine equivalents per day for ≥30 days before surgery)
  • Severe hepatic encephalopathy or cognitive impairment preventing use of PCA or pain scoring
  • Emergency or re-transplantation surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

istinye University

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

T

Taylan Sahin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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