Comparing External Pancreatic Drainage Versus No Drainage During Pancreaticojejunostomy in Patients With Soft Pancreas After Pancreaticoduodenectomy

What this Trial Is About

This research aims to find the best way to prevent pancreatic fistula, a serious complication after pancreatoduodenectomy surgery, especially in patients with a soft pancreas. The study compares the use of an external pancreatic stent during pancreaticojejunostomy to no stent, focusing on long-term clinical outcomes and potential benefits such as reduced complications and hospital stays. Participants are randomly assigned to one of two groups one receives a ureteric catheter stent placed at the pancreaticojejunostomy site, which drains externally through the jejunal loop and abdominal wall the other undergoes pancreaticojejunostomy without any stent. The study monitors effects during and after surgery to assess which method better prevents pancreatic fistula. During the study, participants will be closely monitored for signs of pancreatic fistula within the first week after surgery, with evaluations on days 1, 3, and 5. Additional assessments include checking for intra-abdominal fluid collections during the first two weeks post-operation. Safety and healing outcomes will be tracked until study completion, which is expected to last until September 2026.

External Pancreatic Stent in Pancreaticojejunostomy